Author: Alisa M Higgins, Alistair D Nichol, Ary Serpa Neto, Belinda J Gabbe, Carol L Hodgson, Claire J Tipping, Doug W Gould, Heidi Buhr, Janani Sivasuthan, Jeffrey J Presneill, Kathy Brickell, Meg Harrold, Michael Bailey, Paul J Young, Rinaldo Bellomo, Sally Hurford, Stefan J Schaller, Steven Webb, TEAM Study Investigators and the ANZICS Clinical Trials Group, Tessa Broadley, Theodore J Iwashyna