1. Physiological Sciences

1. Physiology

1. Respiration

1. CNS control of respiration (Feldman JL, McCrimmon DR, Neural Control of Breathing, in Fundamental Neuroscience, 1999 pages 1063-90.)

1. Cardiovascular

a. neuro-cardiac interactions (Sved AF, Cardiovascular System, in Fundamental Neuroscience, 1999 pages 1051-62.)

2. Central and peripheral nervous system (Drummond JC, Patel PM, Cerebral physiology and the effects of anesthetics and techniques, in Anesthesia 5^th Edition, pages 695-734, and Later J, Keep R, Betz AL, Goldstein GW, Blood-Brain-Cerebrospinal fluid barriers, in Basic Neurochemistry 6th Edition, Page 671-89)

1. blood-brain barrier
2. cerebral blood flow
3. cerebral blood volume
4. cerebrospinal fluid
5. cerebral metabolism
6. intracranial pressure
7. nociception

1. Endocrine function (Neuroendocrine Systems I and II, in Fundamental Neuroscience, 1999 pages 1127-87.
2. Temperature regulation (Sessler DI, Temperature Monitoring, in Anesthesia 5^th Edition, pages 1367-1389.

1. Pharmacology (Anesthesia/Miller)

1. General concepts
2. Anesthetics

1. Inhaled

1. halogenated
2. nitrous oxide

1. Intravenous

1. benzodiazepenes
2. narcotics
3. hypotic (misc.)

1. Physical Sciences

1. Anatomy (Youmans)

1. Radiological anatomy of the brain and skull
2. Nervous system

1. Brain
2. Spinal cord and spine
3. Meninges

B. Biochemistry

1. Normal body metabolism
2. Acid-base regulation: buffer systems
3. Water and electrolytes
4. Neurotransmitters (Part 2: Intercellular Signaling, in Basic Neurochemistry, 6^th edition, pages 191-400)

1. catecholamines
2. acetylcholine
3. serotonin
4. histamine
5. glutamate/aspartate
6. GABA/glycine
7. neuropeptides
8. growth factors
9. nitric oxide

1. Intracellular Signaling (Part 3: Intracellular Signaling, in Basic Neurochemistry, 6^th edition, pages 401-536)

1. G proteins
2. phosphoinositides
3. cyclic nuceotides
4. calcium
5. serine and threonine phosphorylation
6. tyrosine phosphorylation

1. Physics

1. Monitoring methods
2. Instrumentation
3. Ventilators

1. Clinical Sciences (Use neuroanesthesia textbooks by Albin, Cottrell, or Cucchiara and neurosurgery textbook by Youmans)

1. Anesthesia procedures, methods and techniques

1. Preoperative evaluation/preparation of a neurosurgical patient

1. coma/stupor
2. cerebral ischemia
3. brain edema

1. Monitoring

1. cardiovascular
2. neurophysiological

1. cortical stimulation

1. venous air embolism
2. cerebral hemodynamics

1. cerebral blood flow
2. intracranial pressure

1. Neuroprotection

1. pharmacology
2. hypothermia

1. Positioning

1. Disease states

1. Cardiovascular

1. cardiopulmonary bypass and brain protection
2. coexisting coronary artery disease in the neurosurgical patient
3. coexisting congenital heart disease in the neurosurgical patient

1. Central nervous system (clinical topics/techniques/scenarios)

1. Neoplasms

1. supratentorial tumors
2. infratentorial tumors (posterior fossa)
3. suprasellar tumors

1. Cerebrovascular disease

1. aneurysms
2. arteriovenous malformation
3. carotid artery disease

1. Epilepsy
2. Functional neurosurgery
3. Spinal cord
4. Pediatric neurosurgery

1. hydrocephalus
2. encephaloceles/myelomeningoceles
3. craniosynostosis
4. craniofacial surgery

1. Radiosurgery
2. Trauma
3. CNS infections

1. Endocrine disorders

1. pituitary disease
2. adrenocortical disease

1. Special problems

1. Radiology

1. angiography
2. invasive radiology
3. CT scan
4. MRI and MRT
5. PET scan

1. Critical care medicine

1. postoperative patient
2. trauma

Recommended Textbooks:

Anesthesia 5^th Edition, edited by.Miller RD, Churchill Livingston (Philadelphia) 2000.

Anesthesia and Neurosurgery, 3^rd Edition, edited by Cottrell JE, and Smith DS, Mosby (St. Louis) 1994, 4^th Edition due late 2000.

Basic Neurochemistry: 6^th Edition, edited by, Siegal GJ, Agranoff BW, Albers RW, Fisher SK, Uhler MD, Lippincott-Raven (Philadelphia) 1999.

Clinical Neuroanesthesia, 2^nd Edition, edited by Cucchiara RF, Black S, Michenfelder JD, Churchill Livington (New York) 1998.

Fundamental Neuroscience: edited by, Zigmond MJ, Bloom FE, Landis SC, Roberts JL, Squire LR, Academic Press (San Diego) 1999.

Textbook of Neuroanesthesia, edited by Albin MS, McGraw Hill (New York) 1996.

Youman's Neurological Surgery: 5^th Edition, edited by H.R. Winn, M.D. Lippincott-Raven (Philadelphia)